Executive Director, Lifecycle Lead

Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company developing cell therapies for patients suffering from autoimmune diseases. Guided by our core values, Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome, we are committed to transforming the future of treatment for autoimmune disease. Join us at the forefront of cell therapy innovation and help redefine what’s possible. Title: Executive Director, Lifecycle Lead Location: Remote (West Coast preferred) Reporting to: Chief Medical & Development Officer The Executive Director, Lifecycle Lead is responsible for leading one or more strategic development programs across the full product lifecycle—from early research and clinical development through process validation (PV/PPQ), commercial readiness, launch, and lifecycle management. This role serves as the cross-functional leader accountable for defining and executing integrated asset strategies that maximize program value and align with Kyverna ’s portfolio and corporate objectives. The Lifecycle Lead partners closely with Research, Translational Sciences, Clinical Development, Regulatory Affairs, Technical Operations, Manufacturing & Supply, Quality, Medical Affairs, Commercial, and Business Development. Responsibilities Lead integrated asset strategy across the full lifecycle, including research, clinical development, PV/PPQ, commercialization, and lifecycle management. Drive strategic planning for emerging therapeutic platform technologies. Evaluate portfolio opportunities and recommend development pathways, platform investments, and lifecycle expansion strategies. Partner with Research, Translational Sciences, and Clinical Development to enable seamless transition from discovery through development. Provide strategic oversight of manufacturing readiness, including process characterization, tech transfer, PV/PPQ, comparability, and supply chain readiness. Ensure alignment across Clinic