Product Quality Lead (APQR & QA CMC Support)

About Genetix Biotherapeutics At Genetix Biotherapeutics every role has meaning, every team member is respected, and every day is a chance to make a difference. When you join Genetix, you're not just landing a new role, you become part of a company that's pursuing curative gene therapies to give patients and their families more days. We are doers, thinkers and collaborators who embrace and live by our values: Our innovation is rooted in the diversity of our teams and results are achieved through cooperation and the integration of multiple viewpoints. This is personal and we approach every challenge with radical care. The Product Quality Lead (APQR & QA CMC Support) is a key member of the QA Compliance organization, responsible for ensuring quality oversight of regulatory submissions and lifecycle management for Genetix Biotherapeutics (GTX) products. This role supports both clinical and commercial programs manufactured or tested at external CMOs and CTOs. The position ensures compliance with US and EU GMP requirements across the full product lifecycle—from development, validation, and tech transfer through clinical/commercial manufacturing and batch disposition. Core responsibilities include providing strategic quality input, technical review of validation and transfer documentation, and oversight of equipment qualification, method validation, and shipping validation activities. This role also leads regulatory impact assessments, annual product quality reviews, and supports escalation management for manufacturing/testing events requiring regulatory interaction. Additionally, the Associate Director partners cross-functionally and with external vendors to support health authority inspection readiness activities, mock inspections and internal audits. This is a full-time hybrid position (3 days a week) in our Somerville – Assembly Row, Massachusetts office. Job Duties/Key Responsibilities Lead quality oversight of GTX product lifecycle activities, ensuring compliance wi