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Senior Research Associate – Scientist II, Molecular Biology & Viral Vector Platforms

Adicet Bio·Worldwide·Redwood City, CA·senior
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JOIN US! Adicet Bio, Inc. is a clinical stage biotechnology company discovering and developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. Adicet is advancing a pipeline of “off-the-shelf” gamma delta T cells, engineered with chimeric antigen receptors (CARs), to facilitate durable activity in patients. For more information, please visit our website at https://www.adicetbio.com . Senior Research Associate – Scientist II, Molecular Biology & Viral Vector Platforms Contract Duration: One year Why this matters: This role accelerates cell and genome therapy research by enabling reliable generation, characterization, and improvement of lentiviral vectors used in discovery and preclinical studies. The Opportunity We are seeking a highly motivated Senior Research Associate / Associate Scientist (BS/MS) to advance lentiviral vector research with some early process development. This is a 100% bench-based, hands-on laboratory role focused on running, troubleshooting, and improving upstream and downstream LVV workflows to enable discovery and preclinical studies. Hands-on, bench role : This position is primarily lab-based and focuses on molecular biology, library design/generation for screening mammalian/phage display or related, lentiviral vector production, and T cell / immune cell workflows. Success in this role requires strong experimental execution, troubleshooting, and clear ELN documentation. Key Responsibilities Design, build, and QC DNA constructs and variant libraries for screening (e.g., mammalian/phage display), including cloning strategy and library design influenced by structure-function analysis. Produce, titer, and QC lentivirus from HEK293T or derivatives; optimize transfection and harvest conditions to improve yield/quality. Perform mammalian tissue culture (maintenance, banking, transfection/transduction) in BSL-2; support scale-up as needed (cell factories and/or single-use bioreactors, where applicable). Execute immune cell