Senior Scientist, Discovery Technologies

What if… you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? Flagship Labs 129 (FL129) is an early-stage biotechnology startup with an ambitious and exciting mission: to develop a technology to facilitate the data generation necessary for training the next generation of generative chemistry models to unlock the future of small molecule drug discovery. FL129 is developing a revolutionary approach to this challenge and is recruiting a team of top-tier scientists to build this powerful and first-in-category platform. This is a unique opportunity to be one of the first employees of a biotech startup that combines an innovative mindset with the resources and know-how of Flagship Pioneering. Position Summary: We are seeking a motivated and highly collaborative Senior Scientist to join FL129’s growing team of experimental and computational scientists to build a novel platform technology. The successful candidate will have strong track record of scientific and technical innovation in molecular biology and small molecule screening, including experience adapting screens to cell- or surface-displayed protein targets. Additional experience with or exposure to yeast surface display, single-cell or genomics methods, and cheminformatics are preferred. The ideal teammate will be highly adaptable, have strong organizational and communication skills, and will thrive in a highly collaborative and multidisciplinary environment. Key Responsibilities: Technology development , aligned with FL129’s core strategic goals. This role is among the first hires, and we’re looking for someone who thinks critically and will influence the company’s scientific direction. Design, construction, and experimental testing of custom target/variant libraries, including binding assays against cell- or surface-displayed protein targets Optimize existing workflows and establish bes